SIAS students Aishani Tewari, Gayatri Tendulkar, and SIAS faculty members Professor S Sivakumar, Dean – Research and Professor, Physics and Dr Kalyan Chakrabarti, Associate Dean (Students) and Associate Professor, Biological Sciences and Chemistry along with Apurva Phale and Ranabir Das from National Center for Biological Sciences, Bangalore have published a paper titled, Analyzing sub-millisecond timescale protein dynamics using eCPMG experiments. The team has designed experiments to measure fast motion in proteins.
How to measure protein motion at 50,000 per second or faster? How much information can we get from the measurements? Extreme Carr-Purcell-Meiboom-Gill (eCPMG) experiments can provide such information, but there are practical considerations. The team has designed a safe and practical measurement scheme. The knowledge of the motion of protein molecules might provide clues about a wide range of diseases, from Cancer to Alzheimer’s.
