R Seshasayee is the past Chairman of IndusInd Bank and currently serves on the Board of Asian Paints Ltd. He is a Chartered Accountant and started his career with Hindustan Lever Ltd. He was the Executive Vice Chairman of Ashok Leyland in 2011, and was Non-Executive Vice Chairman, until July 2016. He has also served on the Boards of Infosys (as Chairman), ICICI Ltd / ICICI Bank and NIT, Tiruchirappalli.

He was the President of the Confederation of Indian Industry (CII) during 2006-07. He was also the President of the Society of Indian Automobile Manufacturers (SIAM), the apex body representing the Indian automobile industry, from 2001-03.

As a member of the Government of India delegations, R Seshasayee was an active participant at the Doha Ministerial Round of WTO in 2001 and the Hong Kong Ministerial Round in 2005. He was also the Co-Chair of the World Economic Forum – Middle East in 2007. Seshasayee has been the Chairman of the Executive Council of the Cancer Institute, Chennai, and Vice President of the Music Academy, Chennai.

He won many honours, including the Lifetime Achievement Award from the Institute of Chartered Accountants of India.